473 MiR-4286 inhibition alters proliferation and apoptosis in melanoma cells
نویسندگان
چکیده
منابع مشابه
Antiproliferative and Pro-Apoptotic Effects of MiR-4286 Inhibition in Melanoma Cells
INTRODUCTION MicroRNAs are essential regulators of gene expression at the post-transcriptional level. Their expression is altered in cancer tissues, and evaluation of these alterations is considered a promising tool used to diagnose and identify prognostic markers. MATERIALS AND METHODS The microRNA expression profiles of formalin-fixed, paraffin-embedded melanoma and melanocytic nevi samples...
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background micrornas are small and non-coding rna molecules with approximately 22 nt in length that cause inhibition of translation or degradation of mrna. mir-155 is a kind of molecule with different functions, such as its role in proliferation, apoptosis, inflammation, differentiation, and immunity. one of its best known functions is apoptosis that affects on caspase-3 activity. the main aim ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2016
ISSN: 0022-202X
DOI: 10.1016/j.jid.2016.06.495